Hepatitis B virus (HBV) replication is controlled by four promoters (preS1, preS2, Cp, and Xp) and two enhancers (EnhI and EnhII).EnhII stimulates Cp activity to regulate the transcriptions of precore, core, polymerase, and pregenomic RNAs, and therefore, EnhII/Cp is essential for the regulation of HBV replication.This study revealed a distinct mec
Background Hemorrhoids are a highly prevalent disease, which have been a health challenge to people for a long time, seriously affecting the life, work, study, and the quality of life.The development of hemorrhoids is closely related to the imbalance of the mucosal barrier function of the anal cushion and the destruction of the mucus barrier and th
All existing data and most of the available materials on Sphyradium doliolum from Ukraine and Moldova are reviewed.The species is reported from 38 localities (some including several sites) on uplands east of the Carpathians, the Dnipro Upland and in the Crimean Mountains.It mostly inhabits the broadleaved forests, but in one locality was found in a
Integrating collaborative data in data-driven Business Shirts Intelligence (BI) system brings an opportunity to foster the decision-making process towards improving tourism competitiveness.This article presents BITOUR, a BI platform that integrates four collaborative data sources (Twitter, Openstreetmap, Tripadvisor and Airbnb).BITOUR follows a cla